Curriculum Vitae

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Advisor

Xihai Zhao, M.D., Ph.D.

Center for Biomedical Imaging Research
Department of Biomedical Engineering

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Personal Data

  • Name:
    • Xihai Zhao
  • Work Address:
    • Room #106, Center for Biomedical Imaging Research (CBIR), Tsinghua University, Haidian District, Beijing 100084, China
  • Date of Birth:
    • August 26, 1974
  • Birthplace:
    • Jixi, Heilongjiang Province, China
  • Citizenship:
    • China

Research Interests and Directions

Link to

Working Experience

  • 05/2019 - now
    • Tenured Associate Professor, Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing 100084, China
  • 09/2015 - now
    • Vice Chair, Department of Radiology, Beijing Tsinghua Changgung Hospital, Beijing 102218, China
  • 09/2013 - now
    • Adjunct Professor, Beijing Institute for Brain Disorders, Beijing 100054, China
  • 12/2015 - 05/2019
    • Tenure-Track Associate Professor, Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing 100084, China
  • 09/2010 - 12/2015
    • Tenure-Track Assistant Professor, Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing 100084, China
  • 09/2007 - 05/2010
    • Senior Research Fellow, Vascular Imaging Lab, Department of Radiology, University of Washington, Seattle 98109, USA.
  • 09/2004 - 08/2007
    • Attending Physician in Radiology, Department of Radiology, Yangzhou People’s First Hospital, Yangzhou 225001, China
  • 08/1999 - 08/2004
    • Resident in Radiology, Department of Radiology, Yangzhou People’s First Hospital, Yangzhou 225001, China

    Awards & Honors

    • 2019
      • E. K. Zavoisky Stipend Award, ISMRM 2019
    • 2018
      • Beijing Science and Technology Award, Third Class
      • E. K. Zavoisky Stipend Award, ISMRM 2018
    • 2017
      • First Prize for Jiangsu Provincial New Technology Import
      • E. K. Zavoisky Stipend Award, ISMRM 2017
    • 2016
      • E. K. Zavoisky Stipend Award, ISMRM 2016
    • 2013
      • E. K. Zavoisky Stipend Award, ISMRM 2013
    • 2012
      • E. K. Zavoisky Stipend Award, ISMRM 2012
    • 2012
      • Jim Pochen Award, SMRA 2012
    • 2011
      • E. K. Zavoisky Stipend Award, ISMRM 2011

    Board Certification

    • 06/27/2004
      • 04041349, Ministry of Personnel People’s Republic of China

    Current License to Practice

    • 24/11/2000
      • 200032110230xxx, Jiangsu Provincial Health Department

    Professional Organizations

    • 02/2019 - now
      • Trainee Committee Member, Society for Magnetic Resonance Angiography (SMRA)
    • 06/2018 - now
      • Academic Board Member, Beijing Institute of Brain Disorders
    • 05/2018 - now
      • Committee Member，Society for Magnetic Resonance Imaging Equipment and Technology of China Association of Medical Equipment (CAME)
    • 05/2018 - now
      • Committee Member，Society for Radiologist of Chinese Medical Doctor Association (CMDA)
    • 05/2017 - now
      • Committee Member，China Chapter of Society for Cardiovascular Magnetic Resonance (SCMR)
    • 06/2015 - now
      • Vice Chairman, Society for Cerebral Blood Flow and Metabolism of Chinese Stroke Association (CSA)
    • 06/2015 - now
      • Committee Member，Society for Translational Medicine of Chinese Stroke Association (CSA)
    • 06/2014 - now
      • Member of the Operating Committee, Cerebrovascular Disease in China National Clinical Research Center for Neurological Diseases
    • 06/2018 - now
      • Member, Society for Cardiovascular Magnetic Resonance (SCMR)
    • 11/2011 - now
      • Member, International Society for Magnetic Resonance in Medicine (ISMRM)
    • 11/2010 - now
      • Member, American Heart Association (AHA)
    • 04/2006 - now
      • Member, Radiological Society of North America (RSNA)

    Editorial Responsibilities

    • Academic Editor for PLoS ONE
    • Editorial Board Member for Neurovascular Imaging
    • Editorial Board Member for Stroke and Vascular Neurology
    • Editorial Board Member for Translational Neuroscience and Clinics
    • Editorial Board Member for Chinese Journal of Medical Imaging
    • Reviewer for Stroke
    • Reviewer for American Journal of Neuroradiology (AJNR)
    • Reviewer for Journal of Magnetic Resonance Imaging (JMRI)
    • Reviewer for Magnetic Resonance Imaging (MRI)
    • Reviewer for European Radiology
    • Reviewer for Biomedical Research International
    • Reviewer for Aging and Disease
    • Reviewer for BMC Cardiovascular Disorders
    • Reviewer for Journal of International Medical Research
    • Reviewer for Chinese Journal of Medical Imaging
    • Reviewer for Chinese Journal of Magnetic Resonance Imaging

    Research Funding

    Onging

    • 2018-2021
      • Project Name: Development and clinical application of multiparametric quantitative MR imaging for carotid artery vulnerable atherosclerotic plaques.
      • Funding Resource: Natural Science Foundation of China (NSFC 81771825), 700K CNY / 100K USD
      • Role: Principle Investigator
      • Overall Goals: This study aims to develop three-dimensional multiparametric quantitative MR imaging technique which enables accurately measuring the T1, T2 and T2* values of carotid plaques via a single imaging sequence. The risk of carotid plaques will be stratified by this multiparametric MR imaging and its predictive value for future ischemic cerebrovascular events will be investigated as well.
    • 2018-2019
      • Project Name: Early diagnosis of asymptomatic alcoholic cardiomyopathy using quantitative MR and C11-acetate PET imaging.
      • Funding Resource: Philips Research Grant, 210K CNY / 30K USD
      • Role: Principle Investigator
      • Overall Goals: This study aims to characterize damage of myocardial tissues and metabolism in asymptomatic subjects with chronic alcohol consumption using quantitative MR imaging and C11-acetate PET imaging.
    • 2017-2021
      • Project Name: Development of MR imaging techniques for assessing vulnerability of intra- and extracranial large artery stenosis.
      • Funding Resource: National Key Research and Development Plan in 13th Five-Year, Ministry of Science and Technology of China (2017YFC1307904), 2,000K CNY / 285K USD
      • Role: Principle Investigator
      • Overall Goals: This study aims to develop, optimize and validate high resolution multicontrast 3D MR vessel wall imaging techniques for assessing the vulnerability of intra- and extracranial carotid large artery stenosis.
    • 2017-2021
      • Project Name: Intracranial artery stenosis MR imaging: etiology and risk factors for progression
      • Funding Resource: Beijing Municipal Science and Technology Commission (D171100003017003), 2,700K CNY / 386K USD
      • Role: Principle Investigator
      • Overall Goals: This study aims to investigate the etiology of intracranial artery stenosis and risk factors for intracranial atherosclerotic plaque progression in recent stroke patients.

    Completed

    • 2013-2016
      • Project Name: Technical development and clinical application of 3D MR vessel imaging from aortic arch to intracranial artery.
      • Funding Resource: Natural Science Foundation of China (NSFC 81271536), 700K CNY / 100K USD
      • Role: Principle Investigator
      • Overall Goals: In this study, using the new developed 3D vessel wall imaging techniques and a new designed and optimized 36-channel neurovascular coil by our group, we plan to investigate the prevalence of vulnerable plaques at the upstream vascular beds of brain. The relationship of vulnerable plaques at these vascular beds with cerebral ischemic lesions will be also evaluated. By doing this study, a 'one-stop-shop' imaging protocol in detecting the culprit lesions of patients with ischemic stroke will be achieved.
    • 2012-2015
      • Project name: Epidemiological investigation of cerebrovascular disease, early screening and intervention of high risk patients and the establishment of GCP
      • Funding Resource: National "Twelfth Five-Year" Plan for Science & Technology Support (2011BAI08B01), 210K CNY / 30K USD
      • Role: Key personnel
      • Overall Goals: To establish a GCP for research on cerebrovascular disease, including early screening, clinical intervention and event.
    • 2011-2013
      • Project Name: Characterization of carotid atherosclerotic plaques and recurrent ischemic cerebrovascular events
      • Funding Resource: Foundation of Beijing Municipal Committee of Science and Technology (D111107003111007), 500K CNY / 74K USD
      • Role: Co- Principle Investigator
      • Overall Goals: To assess the predictive value of carotid plaque MR imaging features for recurrent ischemic stroke.
    • 2011-2013
      • Project Name: Multi-parametric imaging for early detection of brain tumor
      • Funding Resource: Roche-Tsinghua Research Funding, 800K CNY / 114K USD
      • Role: Co- Principal Investigator
      • Overall Goals: In this study, we hypothesized that MR imaging techniques enable early detecting brain glioma; and once the BBB is disrupted by BMFU, it is feasible to deliver drugs and monitor the therapy response using MRI. We aim to: 1) investigate effective diagnostic approaches using MRI for early detection of brain glioma; 2) localize the MR imaging biomarkers for early detection of brain glioma; 3) quantify the changes detected from MRI biomarkers along the progression of brain glioma; 4) find the relationship between MRI biomarkers and tumor grade and subtype. 5) explore the feasibility to break down BBB non-invasively and reversibly; 6) develop non-invasive methods to monitor the status of BBB after BMFU was performed; 7) determine therapeutic effect of drugs for brain glioma after breaking down BBB.
    • 2012-2013
      • Project name: Determination of Atherosclerotic Lesion Distribution of multiple vascular beds in Symptomatic Patients Using MR 3D Imaging Sequences and New Designed 36-Channel Neurovascular Coil
      • Funding Resource: Philips research foundation, 300K CNY / 43K USD
      • Role: Principal Investigator
      • Overall Goals: To determine the distribution of high-risk atherosclerotic plaques in multiple vascular beds, such as intracranial carotid artery, extracranial carotid artery, and thoracic aorta, in symptomatic patients.

    Invited talks

    1. “Consensus on Intracranial Artery Vessel Wall Imaging”, Tiantan International Stroke Conference, June 29th, 2018, Beijing, China
    2. “Intracranial Vessel Wall MR Imaging”. ISMRM 25th Annual Meeting & Exhibition, Weekend Educational Course, April 22nd, 2017, Hawaii, USA.
    3. “MR Vessel Wall Imaging Evaluates Cervicocranial Artery Dissection”. 2nd SCMR China Symposium, November 19th, 2016, Beijing, China
    4. “Resuvastatin treatment for symptomatic middle cerebral artery stenosis based on high-resolution magnetic resonance imaging in two years (REALM)”, Tiantan International Stroke Conference, June 26th, 2016, Beijing, China
    5. “Advances in Intracranial Arterial Dissection Imaging”, Tiantan International Stroke Conference, June 26th, 2015, Beijing, China
    6. “Assessment of cerebrovascular dissection using MR vessel wall imaging”, Tiantan International Stroke Conference, June 27th, 2014, Beijing, China
    7. Assessment of craniocervical arterial dissection by magnetic resonance vessel wall imaging, 7th International Conference on Intracranial Atherosclerosis, Sepember 19th, 2014, Chengdu, China
    8. “Cerebrovascular plaque imaging and stroke risk: does the information beyond the luminal stenosis matter?” The Chinese University of Hong Kong Symposium on Blood Flow and Biomedical Engineering, February 21st, 2014, Hong Kong
    9. “Plaque Imaging: Why Viewing the Wall Matters”, American Heart Association Scientific Sessions, November 18th, 2013, Dallas, USA
    10. “Advances in Magnetic Resonance Vascular Imaging of Ischemic Stroke”, Tiantan International Stroke Conference, June 29th, 2012, Beijing, China
    11. “Relationship of Carotid Atherosclerotic Plaque and Ischemic Stroke: A High Resolution, Black-Blood Vessel Wall MR Imaging Study”, Tiantan International Stroke Conference, June 24th, 2011, Beijing, China
    12. “Relationship of Atherosclerotic Diseases in Multiple Vascular Beds: A 3.0 T MR Plaque Imaging Study”, Advances of MR Plaque Imaging Workshop, 2010, Beijing, China
    13. “Clinical implication of coronary Magnetic resonance angiography” Cardiovascular Magnetic Resonance Imaging Workshop, 2007, Beijing, China
    14. “Examination techniques and imaging diagnosis of MSCT for small bowel diseases” and “Diagnostic value of MSCT water enema for large bowel diseases”, 3rd National continuing medical education on MDCT, 2006, Beijing, China
    15. “Following up study after coronary artery bridge graft operation by 64-slice MDCT”, Siemens MDCT seminar on Clinical Application of 64-slice MDCT, 2006, Beijing, China
    16. “Imaging findings of FNH in liver: comparing with histopathology”, 2nd National continuing medical education on MDCT, 2005, Beijing, China

    Session organizer/moderator of conferences

    Moderator

    • Session: Vascular Imaging: Lumen, Vessel Wall & Function, ISMRM 25th Annual Meeting & Exhibition, April 26th, 2017, Hawaii, USA.
    • Session: MR vascular imaging: from lumen the vessel wall, Tiantan International Stroke Conference, 2012-2018, Beijing, China
    • Session: Cerebrovascular imaging, Annual meeting of Society for Cerebral Blood Flow and Metabolism of Chinese Stroke Association (CSA), 2016-2018, Shijiazhuang, Guangzhou, and Nanjing, China

    Organizer

    • Session: MR vascular imaging: from lumen the vessel wall, Tiantan International Stroke Conference, 2012-2018, Beijing, China
    • Session: Cerebrovascular imaging, Annual meeting of Society for Cerebral Blood Flow and Metabolism of Chinese Stroke Association (CSA), 2016-2018, Shijiazhuang, Guangzhou, and Nanjing, China

     

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